1
9
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82474 | Empasiprubart | ARGX-117 | |
Empasiprubart (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. It inhibits the formation of C3 proconvertase, obstructing classical and lectin pathway activation by binding to the Sushi-2... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00686 | Complement C2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1. | |||
TMPK-01268 | Complement C2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to health... | |||
TMPY-03447 | Complement C2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Complement C2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is P21180-1. | |||
TMPY-00687 | Complement C2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Complement C2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110 kDa and the accession number is P06681-1. | |||
TMPH-02603 | C1SB Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. | |||
TMPH-03326 | MASP2 Protein, Rat, Recombinant (His) | Rat | Baculovirus Insect Cells |
Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the ... | |||
TMPJ-01064 | Serpin G1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement sy... | |||
TMPY-06585 | C1s Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex comp... | |||
TMPJ-00980 | Complement Factor MASP3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of micro... |